Pilot Project Leaders

Active

Travis Hughes

Travis Hughes

Department of Biomedical & Pharmaceutical Sciences
Research area: Determination of the “off” structural state of peroxisome proliferator-activated receptor γ (PPARγ)

J. Stephen Lodmell

J. Stephen Lodmell

Division of Biological Sciences
Research area: The role of Tra2-β1 in splice site selection during RVFV infection

Kendal Ryter

Kendal Ryter

Department of Chemistry and Biochemistry
Research area: TLR4 Agonist/Antagonist Binding in Murine TLR4/MD2 Receptor Complex

Oliver Serang

Oliver Serang

Department of Computer Science
Research area: Graphical models for genomics and proteomics

Previously funded

Bruce E. Bowler

Department of Chemistry & Biochemistry
Research area: Measuring biases in the denatured state ensemble of the three-helix bundle fold

Richard Bridges

Department of Biomedical & Pharmaceutical Sciences
Research area: Molecular Specificity of System Xc- Substrates

Richard Bridges

Department of Biomedical & Pharmaceutical Sciences
Co-Project Leader: 
Sarj Patel, Dept of Biomedical & Pharmaceutical Sciences
Research area: Structure-function of the system xc- glutamate/cystine exchanger: Identification of xct residues participating in binding and translocation

Kasper Hansen

Department of Biomedical & Pharmaceutical Sciences
Research area: Resolving the subunit composition of NMDA receptors in live cells

Michael Kavanaugh

Department of Biomedical and Pharmaceutical Sciences; Director, Center for Structural and Functional Neuroscience
Research area: Biophysical mechanisms of glutamate transport

J. Stephen Lodmell

Division of Biological Sciences
Research area: Characterization of virus-triggered isoforms of RIOK3, a host antiviral protein

J. Stephen Lodmell

Division of Biological Sciences
Research area: Mechanism of novel inhibitors of Rift Valley fever virus nucleocapsid-RNA interactions

Brooke Martin

Department of Chemistry and Biochemistry
Co-Project Leader: Kent Sugden, Department of Chemistry and Biochemistry
Co-Project Leader: 
Katie Hailer, Department of Chemistry, Montana Tech of the University of Montana
Research area: The role of the endonuclease VIII (nei) operon in processing of DNA damage and cell survival

Michele McGuirl

Division of Biological Sciences
Co-Project Leader: Lara M. Taubner, Division of Biological Sciences
Research area: Structural and physiologic consequences of native post-translational modifications of the prion protein: a mechanism for toxicity

Michael F. Minnick

Division of Biological Sciences
Research area: Structural and functional analysis of a unique, metal-binding surface protein of Coxiella burnetii

Jack Nunberg

Division of Biological Sciences
Research area: Arenavirus envelope glycoprotein nanodiscs for cryoEM structural analysis

Christopher Palmer

Department of Chemistry and Biochemistry
Research area: Nanodisc Affinity Capillary Electrophoresis: Characterizing binding to lipid bilayers

Brent Ryckman

Division of Biological Sciences
Research area: Structure-function analysis of a cytomegalovirus CC chemokine

Monica Serban

Department of Biomedical & Pharmaceutical Sciences
Research area: The interplay between the silk fibroin (SF) protein structure and its adhesive properties

Andrea Stierle

Dept. of Biomedical and Pharmaceutical Sciences
Co-Project Leader: Donald Stierle, Dept. of Biomedical and Pharmaceutical Sciences
Co-Project Leader: 
Teri Girtsman, Dept. of Biomedical and Pharmaceutical Sciences
Research area: The use of caspase-1 inhibition and the mitigation of interleukin-1β production by induced inflammasomes to isolate compounds with anti-inflammatory and anticancer activity from symbiotic bacteria of the human gut microbiome

Celestine J. Thomas

Division of Biological Sciences
Co-Project Leader: Jack Nunberg, Montana Biotechnology Center
Research area
: Characterization of liposome fusion by a fusion-active Arenavirus envelope glycoprotein

Ekaterina Voronina

Division of Biological Sciences
Research area: Dissecting the determinants of phase separation and function of stem cell regulator FBF-2

Travis Wheeler

Department of Computer Science
Research area: Reducing false sequence annotation due to alignment overextension and repeats