The Division of Biological Sciences
Dr. Patrick Secor and the Center for Translational Medicine land a major award from the National Institutes of Health
Dr. Secor and collaborators from the new UM Center for Translational Medicine have been funded to try a new approach to develop a vaccine to fight the pernicious and persistent bacterium Pseudomonas aeruginosa. This microbe has rapidly evolved to become multi-drug resistant and is an increasing problem for patients who have compromised immune function or a preexisting traumatic injury or disease. Their approach is to target the vaccine to a specific bacteriophage that commonly infects Pseudomonas and actually makes it LESS susceptible to antibiotics. Preliminary data suggest that this approach may work; the grant is to refine the method and demonstrate its effectiveness and specificity in combatting Pseudomonas infections.