Recent Publications

Dalu Xu, Ashwini Joglekar, Antionette L. Williams, and Jesse C. Hay. 2000. Subunit Structure of a Mammalian ER/Golgi SNARE Complex. Journal of Biological Chemistry 275:39631-39639.

Jesse C. Hay. 2001. SNARE Complex Structure and Function. Experimental Cell Research 271:10-21.

Haruki Hasegawa, Sara Zinsser, Yeyoung Rhee, Einar Osland Vik-MO, Svend Davanger, and Jesse C. Hay. 2003. Mammalian Ykt6 is a Neuronal SNARE Targeted to a Specialized Compartment by its Profilin-like Amino Terminal Domain. Molecular Biology of the Cell 14:698-720.

Ashwini Joglekar, Dalu Xu, Daniel Rigotti, Robert Fairman, and Jesse C. Hay. 2003. The SNARE Motif Contributes to rbet1 Intracellular Targeting and Dynamics Independently of SNARE Interactions. Journal of Biological Chemistry 278:14121-14133.

Antionette L. Williams, Sebastian Ehm, Noëlle C. Jacobson, Dalu Xu and Jesse C. Hay. 2004. Rsly1 Binding to Syntaxin 5 is Required for ER to Golgi Transport but Does Not Promote SNARE Motif Accessibility.  Molecular Biology of the Cell 15: 162-175.

Haruki Hasegawa, Zhifen Yang, Leif Oltedal, Svend Davanger and Jesse C. Hay. 2004. Intramolecular Protein-Protein and Protein-Lipid Interactions Control the Conformation and Subcellular Targeting of Neuronal Ykt6.  J. Cell Science 117:4495-4508.

Dalu Xu and Jesse C. Hay.  2004.  In Vitro Reconstitution of COPII Vesicle Fusion to Generate a Pre-Golgi Intermediate CompartmentJournal of Cell Biology 167:997-1003.

Akira Honda, Omayma S. Al-Awar, Jesse C. Hay, and Julie G. Donaldson. 2005. Targeting of Arf-1 to the Golgi by Membrin, and ER-Golgi SNARE. Journal of Cell Biology, 168:1039-1051.

Ashwini Joglekar and Jesse C.Hay. 2005. Evidence for Regulation of ER/Golgi SNARE Complex Formation by hsp Chaperones in vitro. European Journal of Cell Biology 84:529-542.

Dalu Xu and Jesse C. Hay. 2006. Intracellular Membrane Fusion. In Protein Trafficking: Mechanisms and Regulation. Nava Segev, editor. Landes Scientific Press.

Sidney Yu, Ayano Satoh, Marc Pypaert, Karl Mullen, Jesse C. Hay, and Susan Ferro-Novick. 2006. MBet3p is Required for Homotypic COPII Vesicle Tethering in Mammalian Cells. Journal of Cell Biology 174:359-368.

Marvin Bentley, Yingjian Liang, Karl Mullen, Dalu Xu, Elizabeth Sztul, and Jesse C. Hay. 2006. SNARE Status Regulates Tether Recruitment and Function in Homotypic COPII Vesicle Fusion. Journal of Biological Chemistry 281:38825-38833.

Huaqing Cai, Sidney Yu, Shekar Menon, Yiying Cai, Darina Lazarova, Chunmei Fu, Karin Reinisch, Jesse C. Hay, and Susan Ferro-Novick. 2007. TRAPPI Tethers COPII Vesicles by Binding the Coat Subunit Sec23. Nature 445:941-944.

Jesse C. Hay.  2007.  Calcium: a Fundamental Regulator of Membrane Fusion? EMBO Reports 8:236-240.

Marvin Bentley, Deborah Nycz, Ashwini Joglekar, Ismene Fertschai, Roland Malli, Wolfgang F. Graier, and Jesse C. Hay. 2010. Vesicular Calcium Regulates Coat Retention, Fusogenicity and Size of Pre-Golgi Intermediates. Molecular Biology of the Cell 21:1033-1046. 

Nandhakumar Thianidhi, Jared Helm, Deborah C. Nycz, Marvin Bentley, Yingjian Liang and Jesse C. Hay.  2010.  Alpha-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREsMolecular Biology of the Cell 21:1850-1863.

Meg Trahey and Jesse C. Hay. 2010. Transport Vesicle Uncoating: It's Later Than You Think. F1000 Biology Reports 2:47-52.

Christopher Lord, Deepali Bhandari, Shekar Menon, Majid Ghassemian, Deborah Nycz, Jesse Hay, Pradipta Ghosh, and Susan Ferro-Novick. 2011. Sequential interactions with Sec23 control the direction of vesicle traffic. Nature 473:181-186.

Nandhakumar Thayanidhi, Yingjian Liang, Haruki Hasegawa, Deborah Nycz, Viola Oorschot, Judith Klumperman, and Jesse C. Hay. 2012. R-SNARE YKT6 Resides in Membrane-Associated Protease-Resistant Protein Particles and Modulates Cell Cycle Progression When Over-Expressed. Biology of the Cell 104:397-417.

Meg Trahey, Hyung Suk Oh, Craig E. Cameron, and Jesse C. Hay. 2012. Poliovirus Infection Transiently Increases COPII Vesicle Budding. Journal of Virology 86:9675-9682.

Robert Grabski, Jesse Hay, and Elizabeth Sztul. 2012. Tethering Factor P115: a New Model for Tether-SNARE Interactions. Bioarchitecture 2:1-6.

Deepali Bhandari, Jinzhong Zhang, Shekar Menon, Christopher Lord, Shuliang Chen, Jared R Helm, Kevin Thorsen, Kevin D Corbett, Jesse C Hay, Susan Ferro-Novick.  2013.  Sit4p/PP6 regulates ER-to-Golgi traffic by controlling the dephosphorylation of COPII coat subunits. Molecular Biology of the Cell 24:2727-38.

J. Helm, M. Bentley, K. Thorsen, T. Wang, L. Foltz, J. Klumperman,  J. C. Hay. 2014.  Apoptosis-linked Gene-2/Sec31 Interactions Regulate ER-to-Golgi Transport: a Potential Effector Pathway for Luminal Calcium. Journal of Biological Chemistry 289:23609-28.

Ting Wang, Robert Grabski, Elizabeth Sztul and Jesse C. Hay. 2015. P115-SNARE interactions: a dynamic cycle of P115 binding monomeric SNARE motifs and releasing assembled bundlesTraffic 15:148-171.

Ting Wang and Jesse C. Hay. 2015. Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease. Frontiers Neuroscience 9:433.

Mariah Rayl, Mishana Truitt, Aaron Held, John Sargeant, Kevin Thorsen, and Jesse C. Hay. 2016. Peflin is a Negative Regulator of ER-to-Golgi TransportPLoS one, 11(6):e0157227.