New Study Published

Cover of Journal of virology

Links differences in the infectivity and tropsim between strains of HCMV to the levels of specific glycoprotein complexes in their envleopes. Because these glycoprotein complexes are prime targets of the immune system, and of vaccine stratagies these studies are important as they help address the phenotypic diversity of HCMV.

Zhou M, Lanchy J.M, Ryckman B.J.

Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism.

Journal of Virology  Vol. 89(17):8999-9009.