Jean-Marc Lanchy

Jean-Marc Lanchy

Research Assistant Professor

Email: jean-marc.lanchy(at)
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Curriculum Vitae

Current Position





Former student at the Ecole Normale Sup�rieure, Lyon, France, 1989-1994


Degree of Advanced Studies in Molecular and Cellular Biology,
Universit� Louis Pasteur, Strasbourg, France, 1994


Ph.D. in Molecular Biology, Universit� Louis Pasteur, Strasbourg, France, 1998

Research Interests


Field of Study

Retroviral RNA structure and function

Selected Publications

Baig, T.T., Lanchy, J.-M. & J.S. Lodmell (2007). HIV-2 RNA dimerization is regulated by intramolecular interactions in vitro. RNA�in revision.


Lanchy, J.-M. & J.S. Lodmell (2007). An extended stem-loop 1 is necessary for Human Immunodeficiency Virus type 2 replication and affects genomic RNA encapsidation. Journal of Virology in press.


Lanchy, J.-M., Szafran, Q., Lodmell, J.S. (2004).�Splicing affects presentation of RNA dimerization signals in HIV-2 in vitro. Nucl. Acids Res. 32 (15): 4585-95.


Lanchy, J.-M., Ivanovitch, J.D., Lodmell, J.S. (2003). A Structural Linkage Between the Dimerization and Encapsidation Signals in HIV-2 Leader RNA. RNA. 9 (8): 1007-18.


Deer, E.L., Douk, B., Lanchy,
J.-M., Lodmell, J.S. (2003). Elucidation and Characterization of Oligonucleotides-Accessible Sites on HIV-2 Leader Region RNA. Antisense Nucl. Acid Drug Dev. 13 (1): 45-56.


Lanchy, J.-M., Rentz, C.A., Ivanovitch, J.D., Lodmell, J.S. (2003).Elements Located upstream and downstream of the Major Splice Donor Site Influence the Ability of HIV-2 Leader RNA To Dimerize in Vitro. Biochemistry. 42 (3): 2634-42.


Lanchy, J.-M. & J.S. Lodmell (2002). Alternate usage of two dimerization initiation sites in HIV-2 viral RNA in vitro. J. Mol.Biol. 319 (3): 637-48.


Lanchy, J.-M., Isel, C., Keith, G., Le Grice, S.F.J., Ehresmann, C., Ehresmann, B., Marquet, R. (2000). Dynamics of the HIV-1 reverse transcription complex during initiation of DNA synthesis. J. Biol. Chem. 275 (16): 12306-12312.


Lanchy, J.-M., Keith, G., Le Grice, S.F.J., Ehresmann, B., Ehresmann, C., Marquet, R. (1998). Contacts between reverse transcriptase and the primer strand govern the transition from initiation to elongation of HIV-1 reverse transcription. J. Biol. Chem. 273 (38): 24425-24432.


Lanchy, J.-M., Ehresmann, C., Le Grice, S.F.J., Ehresmann, B., Marquet, R. (1996). Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription. EMBO J. 15 (24): 7178-7187.



Specialized Skills


Teaching Experience


Professional Experience


International Experience



Member of the RNA Society (since March 2006).