People

Patrick Secor

Patrick Secor

Assistant Professor

Office: HS103A
Email: patrick.secor@mso.umt.edu

Personal Website

Education

Postdoctoral Fellow, University of Washington

PhD, Montana State University

BS, Montana State University

Research Interests

Host-pathogen interactions, bacterial stress responses, macromolecular crowding, Pseudomonas aeruginosa

Selected Publications

For a complete list and links to my publications, see this link.

Secor PR*, Sass G, Nazik H, Stevens DA. Effect of acute predation with bacteriophage on intermicrobial aggression by Pseudomonas aeruginosa. PLoS One. 2017 Jun 16;12(6):e0179659. doi: 10.1371/journal.pone.0179659. PubMed PMID: 28622385

Secor, P.R.*, Michaels, L.A., Smigiel, K.S., Rohani, M.G., Jennings, L.K., Hisert, K.B., Arrigoni, A., Braun, K.R., Birkland, T.P., Hallstrand, T.S., Lai, Y., Bollyky, P.L., Singh, P.K., Parks, W.C. (2017) Filamentous bacteriophage produced by Pseudomonas aeruginosa alters the inflammatory response and promotes non-invasive infection in vivo. Infection and Immunity, vol. 85, issue 1. Featured on journal cover.

Penner, J.C., Ferreira, J.A.G., Secor, P.R., Sweere, J.M., Birukova, M.K., Joubert, L.M., Haagensen, J.A.J., Garcia, O., Malkovskiy, A.V., Kaber, G., Nazik, H., Manasherob, R., Spormann, A.M., Clemons, K.V., Stevens, D.A., Bollyky, P.L. (2016) Pf4 Bacteriophage Produced by Pseudomonas aeruginosa Inhibits Aspergillus fumigatus Metabolism via Iron Sequestration. Microbiology, 162, 1583-1594.

Secor, P.R.*, Jennings, L.K., Michaels, L.A., Sweere, J.M., Singh, P.K., Parks, W.C., Bollyky, P.L. (2016) Biofilm assembly becomes crystal clear – filamentous bacteriophage organize the Pseudomonas aeruginosa biofilm matrix into a liquid crystal. Microbial Cell, 3(1): 49-52. Featured on journal cover.

Secor, P.R.*, Sweere, J.M., Michaels, L.A., Malkovskiy, A.V., Lazzareschi, D., Katznelson, E., Rajadas, J., Birnbaum, M.E., Arrigoni, A., Braun, K.R., Evanko, S.P., Stevens, D.A., Kaminsky, W., Singh, P.K., Parks, W.C., Bollyky, P.L. (2015) Filamentous Bacteriophage Promote Biofilm Assembly and Function. Cell Host & Microbe, 18(5): 549-59.

Jennings L.K., Storek K.M., Ledvina H.E., Coulon C., Marmont L.S., Sadovskaya I., Secor, P.R., Tseng B.S., Scian M., Filloux A., Wozniak D.J., Howell P.L., Parsek M.R. (2015) Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix. Proc Natl Acad Sci USA, 112(36): 11353-8.

Secor, P. R.*, Jennings, L. K., James, G. A., Kirker, K. R., Pulcini, E. D., McInnerney, K., Gerlach, R., Livinghouse, T., Hilmer, J. K., Bothner, B., Fleckman, P., Olerud, J. E., Stewart, P. S. (2012) Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression, PLoS One 7(7) e40973.

Secor, P. R.*, James, G. A., Fleckman, P., Olerud, J. E., McInnerney, K., and Stewart, P.S. (2011) Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, MAPK phosphorylation, and cytokine production in human keratinocytes. BMC Microbiol, 11:143.

Kirker, K.R., Secor, P.R., James, G.A, Fleckman, P., Olerud, J.E., Stewart, P.S., (2009) Loss of viability and induction of apoptosis in human keratinocytes exposed to Staphylococcus aureus biofilms in vitro. Wound Repair Regen, 17(5): 690-9.

Dowd, S.E., Sun, Y., Secor, P.R., Rhoads, D.D., Wolcott, B.M., James, G.A., Wolcott, R.D. (2008) Survey of bacterial diversity in chronic wounds using pyrosequencing, DGGE, and full ribosome shotgun sequencing. BMC Microbiol, 8: 43.

James, G.A., Swogger, E., Wolcott, R., Pulcini, E., Secor, P.R., Sestrich, J., Costerton, J.W., Stewart, P.S. (2008) Biofilms in chronic wounds. Wound Repair Regen, 16(1): 37-44.